OPTIMIZATION OF PRECISION AND THROUGHPUT IN MICELLAR ELECTROKINETIC CHROMATOGRAPHY

被引：11

作者：

HAYASHI, Y ^{[1
]}

MATSUDA, R ^{[1
]}

TERABE, S ^{[1
]}

机构：

[1] HIMEJI INST TECHNOL,FAC SCI,KAMIGORI,HYOGO 67812,JAPAN

来源：

CHROMATOGRAPHIA | 1993年 / 37卷 / 3-4期

关键词：

GENERAL CHROMATOGRAPHY; OPTIMIZATION; INFORMATION THEORY; OPTIMIZED RESOLUTION; MEKC;

D O I：

10.1007/BF02275852

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The influences of micelle concentration, applied voltage and temperature on the precision and throughput of analysis are studied. The precision is the Shannon mutual information and the throughput is the transmission speed of the information (= information divided by analysis time). The dependence of the precision and throughput on the peak shape, resolution Rs and run time is examined in various operating conditions. The most precise analysis (indicated by the maximum of the information) and the highest throughput analysis (the maximum of the transmission speed) are selected and their analytical importance is discussed.

引用

页码：149 / 155

页数：7

共 20 条

[1] OPTIMIZATION OF MICELLAR ELECTROKINETIC CHROMATOGRAPHY [J].

FOLEY, JP .

ANALYTICAL CHEMISTRY, 1990, 62 (13) :1302-1308

[2] OPTIMIZATION THEORY OF CHROMATOGRAPHY [J].

HAYASHI, Y ;

MATSUDA, R .

CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, 1993, 18 (01) :1-16

[3] TOTAL CHROMATOGRAPHIC OPTIMIZATION (TOCO) .1. SIMULTANEOUS-OPTIMIZATION OF MANY VARIABLES IN LIQUID-CHROMATOGRAPHY [J].

HAYASHI, Y ;

MATSUDA, R ;

NAKAMURA, A .

CHROMATOGRAPHIA, 1990, 30 (1-2) :85-90

[4] TOTAL CHROMATOGRAPHIC OPTIMIZATION (TOCO) .2. PRECISION AND EFFICIENCY OF ANALYSIS [J].

HAYASHI, Y ;

MATSUDA, R .

CHROMATOGRAPHIA, 1990, 30 (3-4) :171-175

[5] MATHEMATICAL STRUCTURE OF CHROMATOGRAPHIC OPTIMIZATION BASED ON INFORMATION-THEORY .2. ANALYTICAL ROLE OF CHROMATOGRAPHIC VARIABLES [J].

HAYASHI, Y ;

MATSUDA, R .

CHROMATOGRAPHIA, 1991, 31 (7-8) :374-380

[6] MICELLAR ELECTROKINETIC CAPILLARY CHROMATOGRAPHY OF ACIDIC SOLUTES - MIGRATION BEHAVIOR AND OPTIMIZATION STRATEGIES [J].

KHALEDI, MG ;

SMITH, SC ;

STRASTERS, JK .

ANALYTICAL CHEMISTRY, 1991, 63 (17) :1820-1830

[7]

KONDO J, 1984, OPTIMIZATION TECHNIQ

[8]

KUHR WG, 1990, ANAL CHEM, V62, pR403, DOI 10.1021/ac00211a022

[9] OPTIMIZATION OF PH FOR THE SEPARATION OF ORGANIC-ACIDS IN CAPILLARY ZONE ELECTROPHORESIS [J].

SMITH, SC ;

KHALEDI, MG .

ANALYTICAL CHEMISTRY, 1993, 65 (03) :193-198

[10] ELECTROKINETIC SEPARATIONS WITH MICELLAR SOLUTIONS AND OPEN-TUBULAR CAPILLARIES [J].

TERABE, S ;

OTSUKA, K ;

ICHIKAWA, K ;

TSUCHIYA, A ;

ANDO, T .

ANALYTICAL CHEMISTRY, 1984, 56 (01) :111-113

← 1 2 →