CONVENIENT SYNTHESIS OF A SIMPLE COUMARIN FROM SALICYLALDEHYDE AND WITTIG REAGENT .3. SYNTHESIS OF NITROCOUMARINS

被引：25

作者：

HARAYAMA, T ^{[1
]}

NAKATSUKA, K ^{[1
]}

NISHIOKA, H ^{[1
]}

MURAKAMI, K ^{[1
]}

OHMORI, Y ^{[1
]}

TAKEUCHI, Y ^{[1
]}

ISHII, H ^{[1
]}

KENMOTSU, K ^{[1
]}

机构：

[1] CHIBA UNIV,FAC PHARMACEUT SCI,INAGE KU,CHIBA 263,JAPAN

来源：

HETEROCYCLES | 1994年 / 38卷 / 12期

关键词：

D O I：

10.3987/COM-94-6910

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of nitrosalicylaldehydes (1) with carbethoxymethylenetriphenylphosphorane in Et(2)NPh, in Ph(2)O, and in the absence of solvent (neat) at 210-215 degrees C was investigated. Reaction of 3-nitrosalicylaldehyde (1d) in Et(2)NPh afforded the benzoxazole (6) and the aminocoumarin (3e) along with the expected coumarin (3d). It was clarified that the origin of carbon-unit introduced for the formation of the benzoxazole ring came from the alkyl group of solvent.

引用

页码：2729 / 2738

页数：10