DRUG-THERAPY - NICOTINE MEDICATIONS FOR SMOKING CESSATION

被引:254
作者
HENNINGFIELD, JE [1 ]
机构
[1] JOHNS HOPKINS UNIV, SCH MED, DEPT PSYCHIAT & BEHAV SCI, BALTIMORE, MD 21205 USA
关键词
D O I
10.1056/NEJM199511023331807
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cigarettes are among the most addicting products known, and the vast majority of people who quit smoking relapse within days.1,2 In the United States, less than 10 percent of the nearly 20 million people who quit smoking for a day remain abstinent one year later.3 Thus, only 2 to 3 percent of smokers become nonsmokers each year.3 Medications that contain nicotine enable health care providers to increase markedly the ability of their patients to achieve and sustain tobacco abstinence. This review summarizes the scientific rationale for nicotine medications, to help clinicians optimize their use. Pathophysiology of Nicotine Addiction Clinical. © 1995, Massachusetts Medical Society. All rights reserved.
引用
收藏
页码:1196 / 1203
页数:8
相关论文
共 101 条
[91]   RANDOMIZED CONTROLLED TRIAL OF NASAL NICOTINE SPRAY IN SMOKING CESSATION [J].
SUTHERLAND, G ;
STAPLETON, JA ;
RUSSELL, MAH ;
JARVIS, MJ ;
HAJEK, P ;
BELCHER, M ;
FEYERABEND, C .
LANCET, 1992, 340 (8815) :324-329
[92]   A DOUBLE-BLIND TRIAL OF A NICOTINE INHALER FOR SMOKING CESSATION [J].
TONNESEN, P ;
NORREGAARD, J ;
MIKKELSEN, K ;
JORGENSEN, S ;
NILSSON, F .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1993, 269 (10) :1268-1271
[93]   A DOUBLE-BLIND TRIAL OF A 16-HOUR TRANSDERMAL NICOTINE PATCH IN SMOKING CESSATION [J].
TONNESEN, P ;
NORREGAARD, J ;
SIMONSEN, K ;
SAWE, U .
NEW ENGLAND JOURNAL OF MEDICINE, 1991, 325 (05) :311-315
[94]   EFFECT OF NICOTINE CHEWING GUM IN COMBINATION WITH GROUP-COUNSELING ON THE CESSATION OF SMOKING [J].
TONNESEN, P ;
FRYD, V ;
HANSEN, M ;
HELSTED, J ;
GUNNERSEN, AB ;
FORCHAMMER, H ;
STOCKNER, M .
NEW ENGLAND JOURNAL OF MEDICINE, 1988, 318 (01) :15-18
[95]  
Tonnesen P, 1992, J SMOKING RELATED DI, V3, P241
[96]  
WARANCH HR, 1988, LANCET, V1, P49
[97]  
1990, DHHS CDC908416 DEP H
[98]  
1994, MMWR-MORBID MORTAL W, V43, P745
[99]  
1988, DHHS CDC888406 DEP H
[100]  
1994, DIAGNOSTIC STATISTIC