SPERMINE-MEDIATED CASEIN KINASE II-UPTAKE BY RAT-LIVER MITOCHONDRIA

被引：17

作者：

BORDIN, L

CATTAPAN, F

CLARI, G

TONINELLO, A

SILIPRANDI, N

MORET, V

机构：

[1] UNIV PADUA,IST MED INTERNA,I-35100 PADUA,ITALY

[2] UNIV PADUA,DIPARTIMENTO CHIM BIOL,I-35121 PADUA,ITALY

[3] CNR,CTR STUDIO FISIOL MITOCONDRIALE,PADUA,ITALY

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS | 1994年 / 1199卷 / 03期

关键词：

PHOSPHORYLATION; MITOCHONDRIA; SPERMINE;

D O I：

10.1016/0304-4165(94)90005-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Spermine, ubiquitous intracellular polyamine, is able to promote the transmembrane translocation of casein kinase CKII through the outer membrane of rat liver mitochondria and its binding to more internal mitochondrial structures. These findings suggest that spermine may play a critical role in regulating the subcellular distribution of casein kinase CKII.

引用

页码：266 / 270

页数：5