CHOOSING A CELL FATE - A VIEW FROM THE NOTCH LOCUS

被引:194
作者
ARTAVANISTSAKONAS, S
SIMPSON, P
机构
[1] YALE UNIV,HOWARD HUGHES MED INST,DEPT BIOL,NEW HAVEN,CT 06520
[2] FAC MED STRASBOURG,INSERM,CNRS,UNITE BIOL MOLEC GEN GENET 184,GENET MOLEC LAB,F-67085 STRASBOURG,FRANCE
关键词
D O I
10.1016/0168-9525(91)90264-Q
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
During the development of Drosophila melanogaster, individual cells must make choices between a restricted set of possible fates in order to give rise to spatial patterns composed of different types of differentiated cells. The Notch locus appears to play a central and general role in the regulative events that control the local architecture of the final cellular pattern in several tissues, among them being the central and peripheral nervous systems.
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页码:403 / 408
页数:6
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