UNEXPECTED CIS OPENINGS OF CYCLOPENTADIENE MONOEPOXIDE WITH LITHIUM ACETYLIDES AND DIALKYLALKYNYLALANES

被引：6

作者：

BRIGGS, AJ ^{[1
]}

WALKER, KAM ^{[1
]}

机构：

[1] SYNTEX INC,INST ORGAN CHEM,PALO ALTO,CA 94304

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1990年 / 55卷 / 09期

关键词：

D O I：

10.1021/jo00296a076

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reactions of vinyloxiranes with organometallic compounds have received considerable attention recently,conditions (n-BuLi/hexane) to the silyl-protected acetylide 2b, we were surprised to obtain exclusively the cis-1,4-opening product 5b (in 25% yield)7 rather than the expected trans-1,2-opening product 3b. © 1990, American Chemical Society. All rights reserved.

引用

页码：2962 / 2964

页数：3

共 28 条

[21] GENERAL APPROACH TO PROSTAGLANDINS VIA METHYLENECYCLOPENTANONES - TOTAL SYNTHESIS OF + OR - PROSTAGLANDIN-F2ALPHA [J].