CHIRAL RECOGNITION OF STRUCTURALLY RELATED AMINOALKYLPHOSPHONIC ACID-DERIVATIVES ON AN ACETYLATED BETA-CYCLODEXTRIN-BONDED PHASE

被引：24

作者：

CAMILLERI, P

REID, CA

MANALLACK, DT

机构：

[1] Smith Kline Beecham Pharmaceuticals, The Frythe, Welwyn, AL6 9AR, Herts

来源：

CHROMATOGRAPHIA | 1994年 / 38卷 / 11-12期

关键词：

COLUMN LIQUID CHROMATOGRAPHY; CHIRAL RECOGNITION; AMINOALKYLPHOSPHONIC ACID DERIVATIVES; BETA-CYCLODEXTRIN BONDED PHASES;

D O I：

10.1007/BF02269635

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

An acetylated beta-cyclodextrin column was used to analyse the enantiomeric resolution of a number of aminophosphonic acids. Effects of the structure of these compounds on the extent of separation was examined. Molecular modelling studies were also carried out in an attempt to relate any interaction between the amino and phosphonic acid groups to chiral recognition by the stationary phase.

引用

页码：771 / 775

页数：5

共 6 条

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