ENANTIODIVERGENT AND DIASTEREODIVERGENT SYNTHESIS OF ALL 4 DIASTEREOMERS OF THE 2,6-DISUBSTITUTED 3-PIPERIDINOL CHIRAL BUILDING-BLOCK

被引：40

作者：

TOYOOKA, N ^{[1
]}

YOSHIDA, Y ^{[1
]}

MOMOSE, T ^{[1
]}

机构：

[1] TOYAMA MED & PHARMACEUT UNIV,FAC PHARMACEUT SCI,SUGITANI,TOYAMA 93001,JAPAN

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 21期

关键词：

D O I：

10.1016/0040-4039(95)00661-U

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Enantio- and diastereodivergent synthesis of all four diastereomers of 2,6-disubstituted 3-piperidinol has been achieved. The versatility of these compounds as the chiral building block for alkaloid synthesis has been demonstrated both by total synthesis of iso-6-cassine and by formal synthesis of prosopinine, cassine, and spectaline.

引用

页码：3715 / 3718

页数：4

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