ISOZYME-SPECIFIC ENZYME-INHIBITORS .13. S-[5'(R)-[(N-TRIPHOSPHOAMINO)METHYL]ADENOSYL]-L-HOMOCYSTEINE, A POTENT INHIBITOR OF RAT METHIONINE ADENOSYLTRANSFERASES

被引：12

作者：

VRUDHULA, VM ^{[1
]}

KAPPLER, F ^{[1
]}

HAMPTON, A ^{[1
]}

机构：

[1] FOX CHASE CANC CTR,INST CANC RES,PHILADELPHIA,PA 19111

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1987年 / 30卷 / 05期

关键词：

D O I：

10.1021/jm00388a024

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：888 / 894

页数：7

共 28 条

[1] ARMSTRONG MD, 1957, BIOCH PREP, V5, P91
[2] CHLADEK S, 1964, COLLECT CZECH CHEM C, V29, P214
[3] USE OF ADENINE-NUCLEOTIDE DERIVATIVES TO ASSESS POTENTIAL OF EXO-ACTIVE-SITE-DIRECTED REAGENTS AS SPECIES-SPECIFIC OR ISOZYME-SPECIFIC ENZYME INACTIVATORS .2. ISOZYME-SPECIFIC INACTIVATION OF A MAMMALIAN ENZYME AND ITS SIGNIFICANCE IN POSSIBLE DESIGN OF FETAL ISOENZYME TARGETED ANTI-NEOPLASTIC AGENTS
HAMPTON, A
KAPPLER, F
MAEDA, M
PATEL, AD
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1978, 21 (11) : 1137 - 1140
[4] SPECIES-SPECIFIC OR ISOZYME-SPECIFIC ENZYME-INHIBITORS .4. DESIGN OF A 2-SITE INHIBITOR OF ADENYLATE KINASE WITH ISOENZYME SELECTIVITY
HAMPTON, A
KAPPLER, F
PICKER, D
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1982, 25 (06) : 638 - 644
[5] SPECIES-SPECIFIC OR ISOZYME-SPECIFIC ENZYME-INHIBITORS .6. SYNTHESIS AND EVALUATION OF 2-SUBSTRATE CONDENSATION PRODUCTS AS INHIBITORS OF HEXOKINASES AND THYMIDINE KINASES
HAMPTON, A
HAI, TT
KAPPLER, F
CHAWLA, RR
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1982, 25 (07) : 801 - 805
[6] HOFFMAN JL, 1983, METHOD ENZYMOL, V94, P223
[7] 4'-SUBSTITUTED NUCLEOSIDES .2. SYNTHESIS OF NUCLEOSIDE ANTIBIOTIC NUCLEOCIDIN
JENKINS, ID
VERHEYDEN, JPH
MOFFATT, JG
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1976, 98 (11) : 3346 - 3357
[8] STEREOSELECTIVE SYNTHESIS OF VICINAL DIAMINES FROM ALKENES AND CYANAMIDE
JUNG, SH
KOHN, H
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1985, 107 (10) : 2931 - 2943
[9] SPECIES-SPECIFIC OR ISOZYME-SPECIFIC ENZYME-INHIBITORS .8. SYNTHESIS OF DISUBSTITUTED 2-SUBSTRATE CONDENSATION PRODUCTS AS INHIBITORS OF RAT ADENYLATE KINASES
KAPPLER, F
HAI, TT
ABO, M
HAMPTON, A
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1982, 25 (10) : 1179 - 1184
[10] ISOZYME-SPECIFIC ENZYME-INHIBITORS .11. L-HOMOCYSTEINE-ATP S-C5' COVALENT ADDUCTS AS INHIBITORS OF RAT METHIONINE ADENOSYLTRANSFERASES
KAPPLER, F
HAI, TT
COTTER, RJ
HYVER, KJ
HAMPTON, A
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (06) : 1030 - 1038

← 1 2 3 →