N-TERMINAL SEQUENCE SIMILARITIES BETWEEN COMPONENTS OF THE MULTICATALYTIC PROTEINASE COMPLEX

被引：57

作者：

LILLEY, KS ^{[1
]}

DAVISON, MD ^{[1
]}

RIVETT, AJ ^{[1
]}

机构：

[1] UNIV LEICESTER,DEPT BIOCHEM,LEICESTER LE1 7RH,ENGLAND

来源：

FEBS LETTERS | 1990年 / 262卷 / 02期

关键词：

(Rat liver); Gene family; Multicatalytic proteinase; Protease;

D O I：

10.1016/0014-5793(90)80220-D

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The multicatalytic proteinase complex is a high molecular weight nonlysosomal proteinase which is composed of many different types of subunit. As part of a study of the possible relationships between subunits, polypeptides derived from the multicatalytic proteinase from rat liver have been subjected to N-tenninal amino acid sequence analysis. Although several of the subunits are blocked at their N-termini, sequences have been obtained for 7 of the polypeptides. Each of the 7 sequences is unique but they show considerable sequence similarity, suggesting that the proteins are encoded by members of the same gene family. © 1990.

引用

页码：327 / 329

页数：3

共 23 条

[21] PROSOMES, SMALL CYTOPLASMIC RNP PARTICLES, CONTAIN GLYCOPROTEINS [J].