PATHOPHYSIOLOGY OF VEIN GRAFT FAILURE - A REVIEW

被引:260
作者
DAVIES, MG [1 ]
HAGEN, PO [1 ]
机构
[1] DUKE UNIV,MED CTR,DEPT SURG,VASC BIOL & ATHEROSCLEROSIS RES LAB,DURHAM,NC 27710
关键词
VEIN; VEIN GRAFT; INTIMAL HYPERPLASIA; ATHEROSCLEROSIS; FAILURE; SMOOTH MUSCLE CELL ENDOTHELIUM;
D O I
10.1016/S1078-5884(05)80218-7
中图分类号
R61 [外科手术学];
学科分类号
摘要
Vein bypass grafting is an integral component of cardiovascular surgical practice for both arterial and venous diseases. However; many of these grafts will eventually fail due to either intrinsic or extrinsic causes. This review examines the current understanding and knowledge of venous histology, vein graft pathology and the associated endothelial and smooth muscle cell physiology and pharmacology. In addition, the status of research on the therapeutic control of vein graft intimal hyperplasia and accelerated atherosclerosis is assessed.
引用
收藏
页码:7 / 18
页数:12
相关论文
共 176 条
[41]  
Munro, Chan, Patel, Et al., Intimal hyperplasia: the variable response of the human smooth muscle cell (abstract), XXI World Congress of the International Society for Cardiovasculara Surgery, (1993)
[42]  
Adcock, Vein grafts implantation injury, Journal of Vascular Surgery, 10, pp. 587-589, (1989)
[43]  
Quist, LoGerfo, Prevention of smooth muscle cell phenotypic modulation in vein grafts: a histomorphometric study, J Vasc Surg, 16, pp. 225-231, (1992)
[44]  
Cavaliari, Abebe, Hunter, Et al., University of Wisconsin solution prevents intimal proliferation in canine autogenous vein grafts (abstract), VIIth Annual Meeting of the European Society for Vascular Surgery, (1993)
[45]  
Davies, Hagen, Influence of perioperative storage solutions on long term vein graft function and morphology, Ann Vasc Surg, 8, pp. 150-157, (1994)
[46]  
Gottlob, The preservation of the venous endothelium by a dissection without touching and by an atraumatic technique of vascular anastomosis, Min Chir, 32, pp. 693-700, (1977)
[47]  
Haudenschild, Gould, Quist, LoGerfo, Protection of endothelium in vessel segments excised for grafting, Circulation, 64, pp. 101-107, (1981)
[48]  
LoGerfo, Quist, Cranshaw, Haudenschild, An improved technique for preservation of endothelial morphology in vein grafts, Surgery, 90, pp. 115-124, (1981)
[49]  
LoGerfo, Quist, Cantelmo, Haudenschild, Integrity of vein grafts as a function of initial intimal and media preservation, Circulation, 68, pp. 117-124, (1983)
[50]  
LoGerfo, Haudenschild, Quist, A clinical technique for prevention of spasm of endothelium in saphenous vein grafts, Arch Surg, 119, pp. 1212-1214, (1984)