BINARY ANTIDOTES FOR ORGANO-PHOSPHATE POISONING - APROPHEN ANALOGS THAT ARE BOTH ANTIMUSCARINICS AND CARBAMATES

被引：24

作者：

LEADER, H ^{[1
]}

SMEJKAL, RM ^{[1
]}

PAYNE, CS ^{[1
]}

PADILLA, FN ^{[1
]}

DOCTOR, BP ^{[1
]}

GORDON, RK ^{[1
]}

CHIANG, PK ^{[1
]}

机构：

[1] WALTER REED ARMY INST RES, DEPT APPL BIOCHEM, WASHINGTON, DC 20307 USA

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1989年 / 32卷 / 07期

关键词：

D O I：

10.1021/jm00127a020

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1522 / 1528

页数：7

共 50 条

[11]

CHENG Y, 1973, BIOCHEM PHARMACOL, V22, P3099

[12] ALKALOIDS OF PHYSOSTIGMA VENENOSUM .10. SYNTHESIS AND ANTI-ACETYLCHOLINESTERASE ACTIVITIES OF (+)-PHYSOSTIGMINE AND (+)-PHYSOVENINE [J].

DALE, FJ ;

ROBINSON, B .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1970, 22 (12) :889-&

[13] COMPARATIVE EFFECTS OF APROPHEN, ATROPINE AND BENACTYZINE ON CENTRAL AND PERIPHERAL CHOLINOCEPTORS AND ON ACETYLCHOLINESTERASE [J].

DAWSON, RM ;

FREEMAN, SE ;

PADDLE, BM .

BIOCHEMICAL PHARMACOLOGY, 1985, 34 (09) :1577-1579

[14] A NEW AND RAPID COLORIMETRIC DETERMINATION OF ACETYLCHOLINESTERASE ACTIVITY [J].

ELLMAN, GL ;

COURTNEY, KD ;

ANDRES, V ;

FEATHERSTONE, RM .

BIOCHEMICAL PHARMACOLOGY, 1961, 7 (02) :88-&

[15] RECEPTOR FOR SECRETAGOGUES ON PANCREATIC ACINAR-CELLS [J].

GARDNER, JD ;

JENSEN, RT .

AMERICAN JOURNAL OF PHYSIOLOGY, 1980, 238 (02) :G63-G66

[16]

GORDON RK, 1986, J PHARMACOL EXP THER, V236, P85

[17] MUSCARINIC RECEPTOR SUBTYPES - M1 AND M2 BIOCHEMICAL AND FUNCTIONAL-CHARACTERIZATION [J].

HAMMER, R ;

GIACHETTI, A .

LIFE SCIENCES, 1982, 31 (26) :2991-2998

[18] EFFECT OF ATROPINE AND-OR PHYSOSTIGMINE ON CEREBRAL ACETYLCHOLINE IN RATS POISONED WITH SOMAN [J].

HARRIS, LW ;

HEYL, WC ;

STITCHER, DL ;

MOORE, RD .

LIFE SCIENCES, 1978, 22 (10) :907-910

[19] PROTECTION BY A CARBAMATE AGAINST INACTIVATION OF CHOLINESTERASE AND AGAINST THE INDUCTION OF SUPER-SENSITIVITY OF THE ILEUM TO ACETYLCHOLINE PRODUCED BY REPEATED ADMINISTRATION OF AN ORGANOPHOSPHATE [J].

HAYASHI, E ;

OKUDAIRA, H ;

YAMADA, S .

TOXICOLOGY AND APPLIED PHARMACOLOGY, 1979, 48 (01) :111-116

[20]

JAWDOSIUK M, 1976, FARMACO-ED SCI, V31, P671

← 1 2 3 4 5 →