DETERMINATION OF MEDETOMIDINE, ATIPAMEZOLE MIDAZOLAM IN PIG PLASMA BY LIQUID-CHROMATOGRAPHY MASS-SPECTROMETRY

被引：24

作者：

KANAZAWA, H

NISHIMURA, R

SASAKI, N

TAKEUCHI, A

TAKAI, N

NAGATA, Y

MATSUSHIMA, Y

机构：

[1] UNIV TOKYO,FAC AGR,BUNKYO KU,TOKYO 113,JAPAN

[2] UNIV TOKYO,INST IND SCI,MINATO KU,TOKYO 106,JAPAN

来源：

BIOMEDICAL CHROMATOGRAPHY | 1995年 / 9卷 / 04期

关键词：

D O I：

10.1002/bmc.1130090408

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Medetomidine, atipamezole and midazolam in pig plasma were determined by liquid chromatography-mass spectrometry (LC-MS) with an atmospheric pressure chemical ionization interface system by the use of detomidine as an internal standard. The method was applied to studies of pharmacokinetic behaviour of these drugs.

引用

页码：188 / 191

页数：4

共 6 条

[1] THE DETERMINATION OF TOTAL AND UNBOUND MIDAZOLAM IN HUMAN PLASMA - A COMPARISON OF HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY, GAS-CHROMATOGRAPHY AND GAS-CHROMATOGRAPHY MASS-SPECTROMETRY [J].