SILOXANES - VERSATILE TEMPLATES FOR ACYCLIC STEREOCONTROL - SYNTHESIS OF THE C27-C33 SEGMENT OF RAPAMYCIN

被引：69

作者：

HALE, MR ^{[1
]}

HOVEYDA, AH ^{[1
]}

机构：

[1] BOSTON COLL,DEPT CHEM,CHESTNUT HILL,MA 02167

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 06期

关键词：

D O I：

10.1021/jo00032a007

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Five-membered siloxane rings may be employed to relay asymmetry along an acyclic chain in an efficient manner. Application of this method to the synthesis of the C27-C33 segment of the immunosuppressant rapamycin is reported.

引用

页码：1643 / 1645

页数：3

共 31 条

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