EXTRARENAL INVOLVEMENT IN DIARRHEA-ASSOCIATED HEMOLYTIC-UREMIC SYNDROME

被引：91

作者：

GALLO, GE ^{[1
]}

GIANANTONIO, CA ^{[1
]}

机构：

[1] HOSP ITALIANO BUENOS AIRES,DEPT PEDIAT,RA-1181 BUENOS AIRES,DF,ARGENTINA

来源：

PEDIATRIC NEPHROLOGY | 1995年 / 9卷 / 01期

关键词：

HEMOLYTIC-UREMIC SYNDROME; THROMBOTIC MICROANGIOPATHY; EXTRARENAL INVOLVEMENT;

D O I：

10.1007/BF00858990

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

A review of extrarenal involvement in diarrhoea-associated haemolytic-uraemic syndrome (HUS) is based on 64 of our autopsied patients and an update of the literature. Large bowel pathology was the commonest (29 cases), followed by the central nervous system (21 cases), the heart (19 cases) and the pancreas (19 cases). The severity of systemic involvement was associated with the magnitude of renal compromise and the prognosis of the acute phase. Diarrhoea-associated HUS is described as a multiorgan entity, due to extensive microvascular damage and thrombosis. At present mortality during the acute phase is not confined to renal failure; systemic involvement can also lead to death.

引用

页码：117 / 119

页数：3

共 29 条

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