HIGH-YIELD FORMATION OF ARBUTIN FROM HYDROQUINONE BY CELL-SUSPENSION CULTURES OF RAUWOLFIA-SERPENTINA

被引：32

作者：

LUTTERBACH, R ^{[1
]}

STOCKIGT, J ^{[1
]}

机构：

[1] UNIV MAINZ,LEHRSTUHL PHARMAZEUT BIOL,INST PHARM,STAUDINGER WEG 5,W-6500 MAINZ,GERMANY

来源：

HELVETICA CHIMICA ACTA | 1992年 / 75卷 / 06期

关键词：

D O I：

10.1002/hlca.19920750625

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

High-density cell-suspension cultures of Rauwolfia serpentina cultivated in a nutrition medium optimized for the production of the glucoalkaloid raucaffricine synthesize hydroquinone glycosides from continuously added hydroquinone with a total yield of 23.87 g/l (18 g/l of arbutin and 5.87 g/l of a hydroquinone diglycoside) in 7 days. This arbutin production is by far the highest formation of a natural product by plant-cell-culture systems reported to date.

引用

页码：2009 / 2011

页数：3

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