EPITAXIAL-GROWTH OF PROTEIN CRYSTALS FROM 2-DIMENSIONAL CRYSTALS ON LIPID LAYERS

被引：23

作者：

DARST, SA ^{[1
]}

EDWARDS, AM ^{[1
]}

机构：

[1] MCMASTER UNIV,DEPT BIOCHEM,HAMILTON,ON L8N 3Z5,CANADA

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1995年 / 5卷 / 05期

关键词：

D O I：

10.1016/0959-440X(95)80056-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two-dimensional crystals of proteins formed on lipid layers effectively nucleate the epitaxial growth of three-dimensional protein crystals. Crystals suitable for X-ray crystallography can be grown in this way more rapidly, and using substantially lower concentrations of protein and precipitants, than when using conventional methods.

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页码：640 / 644

页数：5

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