ULTRASTRUCTURAL FEATURES OF ETHANOL-INDUCED CARDIOMYOPATHY IN TURKEY POULTS

被引：18

作者：

CZARNECKI, CM ^{[1
]}

SCHAFFER, SW ^{[1
]}

EVANSON, OA ^{[1
]}

机构：

[1] UNIV S ALABAMA, COLL MED, DEPT PHARMACOL, MOBILE, AL 36688 USA

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY | 1985年 / 82卷 / 04期

关键词：

D O I：

10.1016/0300-9629(85)90509-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Alcoholic cardiomyopathy, characterized by cardiac hypertrophy, was induced in young turkey poults with 5% ethanol. Ultrastructural features included accumulation of glycogen swollen mitochondria, myofibrillar lysis, increased number of lyososomes, dilated sarcoplasmic reticulum and dense myofibers. Similarity of these alterations to those described in human alcoholic cardiomyopathy confirms the usefulness of the turkey poult as an animal model for this disease syndrome.

引用

页码：939 / 943

页数：5

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