ADENOASSOCIATED VIRUS - INTEGRATION AT A SPECIFIC CHROMOSOMAL LOCUS

被引：123

作者：

SAMULSKI, RJ ^{[1
]}

机构：

[1] UNIV PITTSBURGH, PITTSBURGH, PA 15260 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1993年 / 3卷 / 01期

关键词：

D O I：

10.1016/S0959-437X(05)80344-2

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Recent characterization of integration of the human parvovirus, adeno-associated virus, has uncovered the exciting occurrence of targeted integration. Thus far, such specific integration has been found to be unique among the eukaryotic viruses. The molecular details of the steps involved in virus integration are actively being pursued and should yield significant information for our understanding of the mechanisms of DNA transposition.

引用

页码：74 / 80

页数：7