CHIRAL SEPARATION OF BARBITURATES AND HYDANTOINS BY REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY USING A 25 OR 50 MM SHORT ODS CARTRIDGE COLUMN VIA BETA-CYCLODEXTRIN INCLUSION COMPLEXES

被引：18

作者：

ETO, S

NODA, H

NODA, A

机构：

[1] UNIV OCCUPAT & ENVIRONM HLTH,SCH MED,DEPT HOSP PHARM,SANGYO IKA DAIGAKU,1-1 ISEIGAOKA,KITAKYUSHU,FUKUOKA 807,JAPAN

[2] KYUSHU UNIV,FAC PHARMACEUT SCI,HIGASHI KU,FUKUOKA 812,JAPAN

来源：

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS | 1992年 / 579卷 / 02期

关键词：

D O I：

10.1016/0378-4347(92)80389-8

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A high-performance liquid chromatographic method on a 25 or 50 mm short ODS cartridge column has been developed for the resolution of the enantiomers of some optically active barbiturates and hydantoins in human serum. Beta-cyclodextrin was used in the mobile phase. This method also seems to be an easy and effective way to test whether beta-cyclodextrin would be a useful chiral discriminator for a particular racemate.

引用

页码：253 / 258

页数：6

共 10 条

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