CONCENTRATIONS OF CADMIUM AND LEAD IN RENAL-CELL CANCER

The incidence of renal cancer increased during the 1980's in Finland. The influence of environmental factors on carcinogenesis has been discussed in recent years. We determined the concentrations of cadmium and lead in renal tissue in 13 renal cancer patients. The mean concentration of cadmium for women was 9430 mu g/kg ( range 3437 - 13,962 mu g/kg) and for male patients 14,702 mu g/kg ( range 3263 - 21,272 mu g/kg). The mean concentration of lead for women was 73 mu g/kg ( range 41 - 105 mu g/kg) and for male patients 96 mu g/kg ( range 34 - 106 mu g/kg). Our results showed that the mean concentrations of cadmium and lead were-low in the renal cortex of renal cell cancer patients.