DETERMINATION OF ESCIN BASED ON ITS INHIBITORY-ACTION ON LACTOSE CRYSTALLIZATION

被引：2

作者：

GRASES, F

GARCIAFERRAGUT, L

COSTABAUZA, A

PRIETO, R

MARCH, JG

机构：

[1] Department of Chemistry, University of Balearic Islands

来源：

ANALYTICA CHIMICA ACTA | 1994年 / 288卷 / 03期

关键词：

TURBIDIMETRY; CRYSTALLIZATION; ESCIN; LACTOSE; PHARMACEUTICALS;

D O I：

10.1016/0003-2670(94)80139-8

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A sensitive and simple kinetic turbidimetric method for the determination of escin, based on its inhibitory action on the crystallization of lactose, is presented. Supersaturated solutions of lactose were prepared by addition of acetone to a stable aqueous lactose solution. The induction period of the crystallization process was measured turbidimetrically in the absence and presence of escin. The method was applied to the determination of escin in pharmaceutical products.

引用

页码：265 / 269

页数：5

共 12 条

[1] GROWTH AND DISSOLUTION OF ORGANIC-CRYSTALS WITH TAILOR-MADE INHIBITORS - IMPLICATIONS IN STEREOCHEMISTRY AND MATERIALS SCIENCE [J].