SELECTION AND PROPERTIES OF LEISHMANIA-TROPICA RESISTANT TO 10-PROPARGYL-5,8-DIDEAZAFOLATE, AN INHIBITOR OF THYMIDYLATE SYNTHETASE

被引：38

作者：

GARVEY, EP

CODERRE, JA

SANTI, DV

机构：

[1] UNIV CALIF SAN FRANCISCO, DEPT BIOCHEM & BIOPHYS, SAN FRANCISCO, CA 94143 USA

[2] UNIV CALIF SAN FRANCISCO, DEPT PHARMACEUT CHEM, SAN FRANCISCO, CA 94143 USA

来源：

MOLECULAR AND BIOCHEMICAL PARASITOLOGY | 1985年 / 17卷 / 01期

关键词：

D O I：

10.1016/0166-6851(85)90129-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：79 / 91

页数：13

共 11 条

[1] UNSTABLE DNA AMPLIFICATIONS IN METHOTREXATE-RESISTANT LEISHMANIA CONSIST OF EXTRACHROMOSOMAL CIRCLES WHICH RELOCALIZE DURING STABILIZATION
BEVERLEY, SM
CODERRE, JA
SANTI, DV
SCHIMKE, RT
[J]. CELL, 1984, 38 (02) : 431 - 439
[2] RELATIONSHIP OF AMPLIFIED DIHYDROFOLATE-REDUCTASE GENES TO DOUBLE MINUTE CHROMOSOMES IN UNSTABLY RESISTANT MOUSE FIBROBLAST CELL-LINES
BROWN, PC
BEVERLEY, SM
SCHIMKE, RT
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1981, 1 (12) : 1077 - 1083
[3] OVERPRODUCTION OF A BIFUNCTIONAL THYMIDYLATE SYNTHETASE-DIHYDROFOLATE REDUCTASE AND DNA AMPLIFICATION IN METHOTREXATE-RESISTANT LEISHMANIA-TROPICA
CODERRE, JA
BEVERLEY, SM
SCHIMKE, RT
SANTI, DV
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (08): : 2132 - 2136
[4] DIHYDROFOLATE-REDUCTASE - THYMIDYLATE SYNTHASE, A BIFUNCTIONAL POLYPEPTIDE FROM CRITHIDIA-FASCICULATA
FERONE, R
ROLAND, S
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (10): : 5802 - 5806
[5] A BIFUNCTIONAL THYMIDYLATE SYNTHETASE-DIHYDROFOLATE REDUCTASE IN PROTOZOA
GARRETT, CE
CODERRE, JA
MEEK, TD
GARVEY, EP
CLAMAN, DM
BEVERLEY, SM
SANTI, DV
[J]. MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1984, 11 (APR) : 257 - 265
[6] BIOCHEMICAL EFFECTS OF A QUINAZOLINE INHIBITOR OF THYMIDYLATE SYNTHETASE, N-(4-(N-((2-AMINO-4-HYDROXY-6-QUINAZOLINYL)METHYL)PROP-2-YNYLAMINO)BENZOYL)-L-GLUTAMIC ACID (CB3717), ON HUMAN-LYMPHOBLASTOID CELLS
JACKSON, RC
JACKMAN, AL
CALVERT, AH
[J]. BIOCHEMICAL PHARMACOLOGY, 1983, 32 (24) : 3783 - 3790
[7] A POTENT ANTI-TUMOR QUINAZOLINE INHIBITOR OF THYMIDYLATE SYNTHETASE - SYNTHESIS, BIOLOGICAL PROPERTIES AND THERAPEUTIC RESULTS IN MICE
JONES, TR
CALVERT, AH
JACKMAN, AL
BROWN, SJ
JONES, M
HARRAP, KR
[J]. EUROPEAN JOURNAL OF CANCER, 1981, 17 (01) : 11 - 19
[8] MANIATIS T, 1982, MOL CLONING LABORATO
[9] PURIFICATION AND CHARACTERIZATION OF THE BIFUNCTIONAL THYMIDYLATE SYNTHETASE DIHYDROFOLATE REDUCTASE FROM METHOTREXATE-RESISTANT LEISHMANIA-TROPICA
MEEK, TD
GARVEY, EP
SANTI, DV
[J]. BIOCHEMISTRY, 1985, 24 (03) : 678 - 686
[10] GENE AMPLIFICATION IN CULTURED ANIMAL-CELLS
SCHIMKE, RT
[J]. CELL, 1984, 37 (03) : 705 - 713

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