INHIBITION OF SOYBEAN LIPOXYGENASE-1 BY ANACARDIC ACIDS, CARDOLS, AND CARDANOLS

被引：52

作者：

SHOBHA, SV ^{[1
]}

RAMADOSS, CS ^{[1
]}

RAVINDRANATH, B ^{[1
]}

机构：

[1] VITTAL MALLYA RES FDN,BANGALORE 560004,KARNATAKA,INDIA

来源：

JOURNAL OF NATURAL PRODUCTS-LLOYDIA | 1994年 / 57卷 / 12期

关键词：

D O I：

10.1021/np50114a025

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

The inhibitory activity of the title compounds against 15-lipoxygenase (soybean lipoxygenase-1) was examined. Anacardic acid 8'Z-monoene [3] exhibited the highest potency (IC50=50 mu M), followed by cardol 8'Z,11'Z,14'-triene [5] (IC50=60 mu M). Cardol [8] and cardanol [12] were ineffective, while the other unsaturated phenols were of intermediate potency.

引用

页码：1755 / 1757

页数：3

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