SYNTHESIS AND ANTITUMOR AND ANTIVIRAL PROPERTIES OF 5-ALKYL-2'-DEOXYURIDINES, 3',5'-CYCLIC MONOPHOSPHATES, AND NEUTRAL CYCLIC TRIESTERS

被引：19

作者：

BERES, J

BENTRUDE, WG

BALZARINI, J

DECLERCQ, E

OTVOS, L

机构：

[1] UNIV UTAH,DEPT CHEM,SALT LAKE CITY,UT 84112

[2] HUNGARIAN ACAD SCI,CENT RES INST CHEM,H-1525 BUDAPEST,HUNGARY

[3] CATHOLIC UNIV LEUVEN,REGA INST MED RES,B-3000 LOUVAIN,BELGIUM

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1986年 / 29卷 / 04期

关键词：

D O I：

10.1021/jm00154a012

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：494 / 499

页数：6

共 49 条

[1] ANTITUMOR CELL AND ANTIMETABOLIC EFFECTS OF 5-ETHYL-2'-DEOXYURIDINE AND 5'-SUBSTITUTED 5-ETHYL-2'-DEOXYURIDINE DERIVATIVES [J].

BALZARINI, J ;

DECLERCQ, E ;

KIEFER, G ;

KEPPELER, K ;

BUCHELE, A .

INVESTIGATIONAL NEW DRUGS, 1984, 2 (01) :35-47

[2] ROLE OF THYMIDINE KINASE IN THE INHIBITORY ACTIVITY OF 5-SUBSTITUTED-2'-DEOXYURIDINES ON THE GROWTH OF HUMAN AND MURINE TUMOR-CELL LINES [J].

BALZARINI, J ;

DECLERCQ, E ;

TORRENCE, PF ;

MERTES, MP ;

PARK, JS ;

SCHMIDT, CL ;

SHUGAR, D ;

BARR, PJ ;

JONES, AS ;

VERHELST, G ;

WALKER, RT .

BIOCHEMICAL PHARMACOLOGY, 1982, 31 (06) :1089-1095

[3] 5-SUBSTITUTED 2'-DEOXYURIDINES - CORRELATION BETWEEN INHIBITION OF TUMOR-CELL GROWTH AND INHIBITION OF THYMIDINE KINASE AND THYMIDYLATE SYNTHETASE [J].

BALZARINI, J ;

DECLERCQ, E ;

MERTES, MP ;

SHUGAR, D ;

TORRENCE, PF .

BIOCHEMICAL PHARMACOLOGY, 1982, 31 (22) :3673-3682

[4] SYNTHESIS, STRUCTURE, AND ANTITUMOR AND ANTIVIRAL ACTIVITIES OF A SERIES OF 5-HALOURIDINE CYCLIC 3',5'-MONOPHOSPHATES [J].

BERES, J ;

BENTRUDE, WG ;

KALMAN, A ;

PARKANYI, L ;

BALZARINI, J ;

DECLERCQ, E .

JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (04) :488-493

[5] SYNTHESIS AND ANTITUMOR AND ANTIVIRAL ACTIVITIES OF A SERIES OF 1-BETA-D-RIBOFURANOSYL-5-HALOCYTOSINE (5-HALOCYTIDINE) CYCLIC 3',5'-MONOPHOSPHATES [J].

BERES, J ;

BENTRUDE, WG ;

KRUPPA, G ;

MCKERNAN, PA ;

ROBINS, RK .

JOURNAL OF MEDICINAL CHEMISTRY, 1985, 28 (04) :418-422

[6] AN EFFICIENT SYNTHESIS OF CERTAIN 5-SUBSTITUTED-2'-DEOXYURIDINE 3',5'-CYCLIC-MONOPHOSPHATE P-O-ALKYL(ARALKYL) ESTERS - THE CRYSTAL AND MOLECULAR-STRUCTURE OF 5-IODO-2'-DEOXYURIDINE 3',5'-CYCLIC-MONOPHOSPHATE P-O-METHYL ESTER WITH AXIAL METHOXY GROUP [J].

BERES, J ;

SANDOR, P ;

KALMAN, A ;

KORITSANSZKY, T ;

OTVOS, L .

TETRAHEDRON, 1984, 40 (12) :2405-2414

[7]

BERES J, J MED CHEM

[8] PROTON MAGNETIC-RESONANCE STUDY OF CONFORMATIONS OF 3', 5'-CYCLIC NUCLEOTIDES [J].

BLACKBURN, BJ ;

LAPPER, RD ;

SMITH, ICP .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1973, 95 (09) :2873-2878

[9]

BOTTKA S, 1979, TETRAHEDRON, V35, P2909

[10] MASS SPECTROSCOPIC DIFFERENTIATION BETWEEN 3'-NUCLEOSIDE AND 5'-NUCLEOSIDE MONOPHOSPHORIC ACIDS [J].

BUDZIKIEWICZ, H ;

FEISTNER, G .

BIOMEDICAL MASS SPECTROMETRY, 1978, 5 (08) :512-513

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