BINDING OF PO-210 TO LIVER METALLOTHIONEIN

被引：21

作者：

APOSHIAN, HV

BRUCE, DC

机构：

来源：

RADIATION RESEARCH | 1991年 / 126卷 / 03期

关键词：

D O I：

10.2307/3577929

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The interactions of 210Po at the molecular level in biological systems have received little study even though this α-emitting radionuclide occurs widely in nature. Polonium-210 was given subcutaneously to rats and found to be incorporated into liver metallothionein as judged by a number of criteria including heat stability, acetone precipitation, and chromatography. In vitro studies confirmed this binding. The binding of 210Po to metallothionein has implications that may help explain some of the radiation damage 210Po causes intracellularly.

引用

页码：379 / 382

页数：4

共 30 条

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