SEQUENCE-SELECTIVE PEPTIDE BINDING WITH A SYNTHETIC RECEPTOR

被引：77

作者：

YOON, SS

STILL, WC

机构：

[1] Department of Chemistry, Columbia University, New York

来源：

TETRAHEDRON | 1995年 / 51卷 / 02期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/0040-4020(94)00916-I

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A dye-labeled variant of a highly substrate-selective synthetic receptor for peptides is described and its binding selectivity for certain di- and tripeptide sequences is elucidated using an encoded combinatorial library.

引用

页码：567 / 578

页数：12

共 29 条

[21] THE GENERATION OF MOLECULAR DIVERSITY [J].

PAVIA, MR ;

SAWYER, TK ;

MOOS, WH .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1993, 3 (03) :387-396

[22] HOST-GUEST COMPLEXATION .13. HIGH CHIRAL RECOGNITION OF AMINO ESTERS BY DILOCULAR HOSTS CONTAINING EXTENDED STERIC BARRIERS [J].

PEACOCK, SC ;

DOMEIER, LA ;

GAETA, FCA ;

HELGESON, RC ;

TIMKO, JM ;

CRAM, DJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1978, 100 (26) :8190-8202

[23] HYDROPHOBIC BINDING OF WATER-SOLUBLE GUESTS BY HIGH-SYMMETRY, CHIRAL HOSTS - AN ELECTRON-RICH RECEPTOR-SITE WITH A GENERAL AFFINITY FOR QUATERNARY AMMONIUM-COMPOUNDS AND ELECTRON-DEFICIENT PI-SYSTEMS [J].

PETTI, MA ;

SHEPODD, TJ ;

BARRANS, RE ;

DOUGHERTY, DA .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (20) :6825-6840

[24] MOLECULAR RECOGNITION - NEW SHAPES FOR ASYMMETRIC MICROENVIRONMENTS [J].

REBEK, J ;

ASKEW, B ;

BALLESTER, P ;

DOA, M .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1987, 109 (13) :4119-4120

[25] A VERY MILD, CATALYTIC AND VERSATILE PROCEDURE FOR ALPHA-OXIDATION OF KETONE SILYL ENOL ETHERS USING (SALEN)MANGANESE(III) COMPLEXES - A NEW, CHIRAL COMPLEX GIVING ASYMMETRIC INDUCTION - A POSSIBLE MODEL FOR SELECTIVE BIOCHEMICAL OXIDATIVE REACTIONS THROUGH ENOL FORMATION [J].

REDDY, DR ;

THORNTON, ER .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1992, (02) :172-173

[26] HOST GUEST COMPLEXATION .60. RIGIDLY HOLLOW HOSTS THAT ENCAPSULATE SMALL MOLECULES [J].

TANNER, ME ;

KNOBLER, CB ;

CRAM, DJ .

JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (01) :40-46

[27] CHEMISTRY OF SYNTHETIC RECEPTORS AND FUNCTIONAL-GROUP ARRAYS .16. ENANTIOSELECTIVE AND DIASTEREOSELECTIVE MOLECULAR RECOGNITION OF ALICYCLIC SUBSTRATES IN AQUEOUS-MEDIA BY A CHIRAL, RESOLVED SYNTHETIC RECEPTOR [J].

WEBB, TH ;

SUH, HS ;

WILCOX, CS .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (22) :8554-8555

[28]

YOON SS, 1993, J AM CHEM SOC, V115, P832

[29]

YOON SS, 1994, IN PRESS TETRAHEDRON

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