HUMAN OOCYTES EXPRESS MURINE RETROVIRAL EQUIVALENTS

被引：18

作者：

NILSSON, BO

KATTSTROM, PO

SUNDSTROM, P

JAQUEMIN, P

LARSSON, E

机构：

[1] MALMO GEN HOSP,DEPT OBSTET & GYNECOL,S-21401 MALMO,SWEDEN

[2] INST PASTEUR,B-1040 BRUSSELS,BELGIUM

[3] ACAD HOSP UPPSALA,DEPT PATHOL,S-75014 UPPSALA,SWEDEN

来源：

VIRUS GENES | 1992年 / 6卷 / 03期

关键词：

GP70; RETROVIRUS; OOCYTES; HUMAN;

D O I：

10.1007/BF01702561

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Unfertilized human oocytes expressed a gp70-related epitope as observed when staining section immunocytochemically with a panel of monoclonal antibodies against gp70 of murine leukemia virus. Some oocytes also expressed virus-like particles at the cell membrane. Follicular fluids, corresponding to these oocytes, contained p30- and gp70-related antigens, reverse transcriptase, and an increased titer of interferon. The three- to four-cell human cleavage stages did not contain the gp70-related epitope. It is concluded that human oocytes, but not early cleavage stages, express products that suggest the presence of an active endogenous retrovirus genome.

引用

页码：221 / 227

页数：7

共 14 条

[11] THE EXPRESSION OF INTRACISTERNAL-A PARTICLE GENES IN THE PREIMPLANTATION MOUSE EMBRYO [J].