ANALYSIS OF POLYETHERS BY ISOCRATIC HPLC WITH UNIVERSAL DETECTORS .1. OPTIMIZATION OF CHROMATOGRAPHIC CONDITIONS

被引：34

作者：

TRATHNIGG, B ^{[1
]}

THAMER, D ^{[1
]}

YAN, X ^{[1
]}

KINUGASA, S ^{[1
]}

机构：

[1] NATL CHEM LAB IND,TSUKUBA,IBARAKI 305,JAPAN

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY | 1993年 / 16卷 / 12期

关键词：

D O I：

10.1080/10826079308019584

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Polyethylene glycols, their mono- and dimethyl ethers, and polypropylene glycols were analyzed by LAC with coupled density and RI detection on a C-18 column in methanol-water. Depending on the composition of the mobile phase, PEGs up to molecular weights of 3000 and PPGs up to molecular weights of 1000 could be separated. Peaks were identified using monodisperse oligomers as internal standards. Critical conditions for PEG were found at a mobile phase composition of MeOH:H2O 80:20, which allowed a good separation of PPG.

引用

收藏

页码：2439 / 2452

页数：14

相关论文

共 26 条

[11] PREPARATION AND CHARACTERIZATION OF PURE OLIGOETHYLENE GLYCOLS-I [J].

KINUGASA, S ;

HAYASHI, H ;

HATTORI, S .

POLYMER JOURNAL, 1990, 22 (12) :1059-1064

[12] GEL-PERMEATION CHROMATOGRAPHY OF OXYETHYLENE OXYPROPYLENE BLOCK COPOLYMERS [J].

LUO, YZ ;

REDDY, NK ;

HEATLEY, F ;

BOOTH, C ;

GOODWIN, EJ ;

JACKSON, D .

EUROPEAN POLYMER JOURNAL, 1988, 24 (07) :607-610

[13] USE OF AN EVAPORATIVE LIGHT-SCATTERING DETECTOR IN REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY OF OLIGOMERIC SURFACTANTS [J].

MENGERINK, Y ;

DEMAN, HCJ ;

VANDERWAL, S .

JOURNAL OF CHROMATOGRAPHY, 1991, 552 (1-2) :593-604

[14] ANALYSIS OF BENZYLOXY-TERMINATED POLY(1,3,6-TRIOXOCANE)S BY SUPERCRITICAL FLUID CHROMATOGRAPHY [J].

PASCH, H ;

KRUGER, H ;

MUCH, H ;

JUST, U .

JOURNAL OF CHROMATOGRAPHY, 1992, 589 (1-2) :295-299

[15]

Pasch H., 1992, LC GC EUR, V5, P38

[16] DETERMINATION OF FUNCTIONALITY AND MOLECULAR-WEIGHT DISTRIBUTION BY ORTHOGONAL CHROMATOGRAPHY [J].

SCHULZ, G ;

MUCH, H ;

KRUGER, H ;

WEHRSTEDT, C .

JOURNAL OF LIQUID CHROMATOGRAPHY, 1990, 13 (09) :1745-1763

[17]

STANCHER B, 1975, J CHROMATOGR, V111, P549

[18] DETERMINATION OF CHEMICAL-COMPOSITION OF POLYMERS BY SEC WITH COUPLED DENSITY AND RI DETECTION .1. POLYETHYLENE-GLYCOL AND POLYPROPYLENE GLYCOL [J].

TRATHNIGG, B .

JOURNAL OF LIQUID CHROMATOGRAPHY, 1990, 13 (09) :1731-1743

[19] DETERMINATION OF CHEMICAL-COMPOSITION OF POLYMERS BY SIZE-EXCLUSION CHROMATOGRAPHY WITH COUPLED DENSITY AND REFRACTIVE-INDEX DETECTION .3. POLYETHYLENE OXIDE AND POLYTETRAHYDROFURAN [J].

TRATHNIGG, B .

JOURNAL OF CHROMATOGRAPHY, 1991, 552 (1-2) :507-516

[20] NEW UNIVERSAL DETECTOR FOR HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY - THE DENSITY DETECTOR [J].

TRATHNIGG, B ;

JORDE, C .

JOURNAL OF CHROMATOGRAPHY, 1987, 385 :17-23