CONCOMITANT CATALYTIC TRANSFORMATIONS OF GEMINAL ETHYNYL AND HYDROXY-GROUPS OF STEROIDS INTO ACETYL AND ESTER FUNCTIONS WITH RETENTION OF CONFIGURATION BY [RU(MU-O2CH)(CO)(2)(PPH(3))](2)

被引：26

作者：

DARCEL, C

BRUNEAU, C

DIXNEUF, PH

NEEF, G

机构：

[1] UNIV RENNES,CHIM COORDINAT ORGAN LAB,CNRS,URA 415,F-35042 RENNES,FRANCE

[2] SCHERING AG,INST MED CHEM,D-13342 BERLIN,GERMANY

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1994年 / 03期

关键词：

D O I：

10.1039/c39940000333

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Steroids 1, 2, 3 containing both hydroxy and ethynyl groups at C(17) are selectively transformed by reaction with carboxylic acids, catalysed by [Ru(mu-O2CH)(CO)(2)(PPh(3))](2) complex, into beta-oxopropyl esters 4, 5, 6 with retention of configuration.

引用

页码：333 / 334

页数：2

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