LONGITUDINAL-STUDY OF THE CELLULAR-RESPONSE TO PF155 RESA AND CIRCUMSPOROZOITE PROTEIN IN MADAGASCAR

被引：13

作者：

CHOUGNET, C

DELORON, P

LEPERS, JP

RASON, MD

SAVEL, J

COULANGES, P

机构：

[1] UNIV PARIS 05, BIOL PARASITAIRE LAB, F-75270 PARIS 06, FRANCE

[2] INST PASTEUR MADAGASCAR, ANTANANARIVO, MADAGASCAR

来源：

IMMUNOLOGY LETTERS | 1990年 / 25卷 / 1-3期

关键词：

Cellular response; Circumsporozoite protein; Pf155/RESA; Plasmodium falciparum;

D O I：

10.1016/0165-2478(90)90120-F

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In a community follow-up conducted in the Central Highlands of Madagascar, the cellular responses to synthetic peptides from the immunodominant regions of Pf155/RESA and the repeat region of the circumsporozoite protein were studied. Seasonal variations of the T cell response were measured at the individual level; the relationship between this response and the presence of parasites in blood was assessed; the question of the possible protective value of the lymphocyte proliferation in presence of a specific antigen was addressed. © 1990.

引用

页码：231 / 236

页数：6

共 19 条

[11] ANTIBODIES IN MALARIAL SERA TO PARASITE ANTIGENS IN THE MEMBRANE OF ERYTHROCYTES INFECTED WITH EARLY ASEXUAL STAGES OF PLASMODIUM-FALCIPARUM [J].