DIFFERENT REQUIREMENTS FOR MEMBRANE-FUSION MEDIATED BY THE ENVELOPES OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 AND TYPE-2

被引：45

作者：

DRAGIC, T ^{[1
]}

ALIZON, M ^{[1
]}

机构：

[1] INST COCHIN GENET MOLEC,INSERM,U332,22 RUE MECHAIN,F-75014 PARIS,FRANCE

来源：

JOURNAL OF VIROLOGY | 1993年 / 67卷 / 04期

关键词：

D O I：

10.1128/JVI.67.4.2355-2359.1993

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

CD4+ cells derived from the human cell lines U87MG and SCL1 cannot be infected by human immunodeficiency virus type 1 (HIV-1) or fuse with cells expressing the HIV-1 envelope. This block was complemented in heterokaryons with HeLa cells and probably reflects the absence of cellular factors necessary for membrane fusion. Since U87MG cells expressing CD4 are permissive to HIV-2, distinct cellular factors could be required for fusion mediated by two related human retroviruses.

引用

页码：2355 / 2359

页数：5

共 18 条

[1] GENETIC-VARIABILITY OF THE AIDS VIRUS - NUCLEOTIDE-SEQUENCE ANALYSIS OF 2 ISOLATES FROM AFRICAN PATIENTS [J].

ALIZON, M ;

WAINHOBSON, S ;

MONTAGNIER, L ;

SONIGO, P .

CELL, 1986, 46 (01) :63-74

[2] HUMAN-IMMUNODEFICIENCY-VIRUS ENVELOPE GLYCOPROTEIN CD4-MEDIATED FUSION OF NONPRIMATE CELLS WITH HUMAN-CELLS [J].

ASHORN, PA ;

BERGER, EA ;

MOSS, B .

JOURNAL OF VIROLOGY, 1990, 64 (05) :2149-2156

[3] CELLULAR FACTORS REGULATE TRANSACTIVATION OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 [J].

BARRY, PA ;

PRATTLOWE, E ;

UNGER, RE ;

LUCIW, PA .

JOURNAL OF VIROLOGY, 1991, 65 (03) :1392-1399

[4] A 2ND ORIGIN OF DNA PLUS-STRAND SYNTHESIS IS REQUIRED FOR OPTIMAL HUMAN-IMMUNODEFICIENCY-VIRUS REPLICATION [J].

CHARNEAU, P ;

ALIZON, M ;

CLAVEL, F .

JOURNAL OF VIROLOGY, 1992, 66 (05) :2814-2820

[5] IDENTIFICATION OF HUMAN-IMMUNODEFICIENCY-VIRUS ENVELOPE GENE-SEQUENCES INFLUENCING VIRAL ENTRY INTO CD4-POSITIVE HELA-CELLS, T-LEUKEMIA CELLS, AND MACROPHAGES [J].

CHESEBRO, B ;

NISHIO, J ;

PERRYMAN, S ;

CANN, A ;

OBRIEN, W ;

CHEN, ISY ;

WEHRLY, K .

JOURNAL OF VIROLOGY, 1991, 65 (11) :5782-5789

[6] FAILURE OF HUMAN IMMUNODEFICIENCY VIRUS ENTRY AND INFECTION IN CD4-POSITIVE HUMAN-BRAIN AND SKIN CELLS [J].

CHESEBRO, B ;

BULLER, R ;

PORTIS, J ;

WEHRLY, K .

JOURNAL OF VIROLOGY, 1990, 64 (01) :215-221

[7] HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-2 INFECTION AND FUSION OF CD4-NEGATIVE HUMAN CELL-LINES - INDUCTION AND ENHANCEMENT BY SOLUBLE CD4 [J].

CLAPHAM, PR ;

MCKNIGHT, A ;

WEISS, RA .

JOURNAL OF VIROLOGY, 1992, 66 (06) :3531-3537

[8] SPECIFIC CELL-SURFACE REQUIREMENTS FOR THE INFECTION OF CD4-POSITIVE CELLS BY HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 AND TYPE-2 AND BY SIMIAN IMMUNODEFICIENCY VIRUS [J].

CLAPHAM, PR ;

BLANC, D ;

WEISS, RA .

VIROLOGY, 1991, 181 (02) :703-715

[9] ISOLATION OF A NEW HUMAN RETROVIRUS FROM WEST-AFRICAN PATIENTS WITH AIDS [J].

CLAVEL, F ;

GUETARD, D ;

BRUNVEZINET, F ;

CHAMARET, S ;

REY, MA ;

SANTOSFERREIRA, MO ;

LAURENT, AG ;

DAUGUET, C ;

KATLAMA, C ;

ROUZIOUX, C ;

KLATZMANN, D ;

CHAMPALIMAUD, JL ;

MONTAGNIER, L .

SCIENCE, 1986, 233 (4761) :343-346

[10] COMPLEMENTATION OF MURINE CELLS FOR HUMAN-IMMUNODEFICIENCY-VIRUS ENVELOPE CD4-MEDIATED FUSION IN HUMAN MURINE HETEROKARYONS [J].

DRAGIC, T ;

CHARNEAU, P ;

CLAVEL, F ;

ALIZON, M .

JOURNAL OF VIROLOGY, 1992, 66 (08) :4794-4802

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