11-HYDROXYSTAUROSPORINE - A HIGHLY CYTOTOXIC, POWERFUL PROTEIN-KINASE-C INHIBITOR FROM A TUNICATE

被引：61

作者：

KINNEL, RB ^{[1
]}

SCHEUER, PJ ^{[1
]}

机构：

[1] UNIV HAWAII MANOA,DEPT CHEM,2545 THE MALL,HONOLULU,HI 96822

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 23期

关键词：

D O I：

10.1021/jo00049a049

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[No abstract available]

引用

页码：6327 / 6329

页数：3

共 15 条

[1] INHIBITION OF PROTEIN-KINASE-C BY THE TYROSINE KINASE INHIBITOR ERBSTATIN [J].

BISHOP, WR ;

PETRIN, J ;

WANG, L ;

RAMESH, U ;

DOLL, RJ .

BIOCHEMICAL PHARMACOLOGY, 1990, 40 (09) :2129-2135

[2] TJIPANAZOLES, NEW ANTIFUNGAL AGENTS FROM THE BLUE-GREEN-ALGA TOLYPOTHRIX-TJIPANASENSIS [J].

BONJOUKLIAN, R ;

SMITKA, TA ;

DOOLIN, LE ;

MOLLOY, RM ;

DEBONO, M ;

SHAFFER, SA ;

MOORE, RE ;

STEWART, JB ;

PATTERSON, GML .

TETRAHEDRON, 1991, 47 (37) :7739-7750

[3] SHERMILAMINE-A - A PENTACYCLIC ALKALOID FROM A TUNICATE [J].

COORAY, NM ;

SCHEUER, PJ ;

PARKANYI, L ;

CLARDY, J .

JOURNAL OF ORGANIC CHEMISTRY, 1988, 53 (19) :4619-4620

[4] WAKAYIN - A NOVEL CYTOTOXIC PYRROLOIMINOQUINONE ALKALOID FROM THE ASCIDIAN CLAVELINA SPECIES [J].

COPP, BR ;

IRELAND, CM ;

BARROWS, LR .

JOURNAL OF ORGANIC CHEMISTRY, 1991, 56 (15) :4596-4597

[5] THE DESIGN OF INHIBITORS OF PROTEIN-KINASE-C - THE SOLUTION CONFORMATION OF STAUROSPORINE [J].

DAVIS, PD ;

HILL, CH ;

THOMAS, WA ;

WHITCOMBE, IWA .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1991, (03) :182-184

[6] MARINE NATURAL-PRODUCTS [J].

FAULKNER, DJ .

NATURAL PRODUCT REPORTS, 1991, 8 (02) :97-147

[7] X-RAY CRYSTAL-STRUCTURE OF STAUROSPORINE - NEW ALKALOID FROM A STREPTOMYCES STRAIN [J].

FURUSAKI, A ;

HASHIBA, N ;

MATSUMOTO, T ;

HIRANO, A ;

IWAI, Y ;

OMURA, S .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1978, (18) :800-801

[8]

GRIBBLE GW, IN PRESS STUDIES NAT

[9]

KNUBEL G, 1990, J ANTIBIOT, V43, P1236

[10] DISCORHABDIN-D, AN ANTITUMOR ALKALOID FROM THE SPONGES LATRUNCULIA-BREVIS AND PRIANOS SP [J].

PERRY, NB ;

BLUNT, JW ;

MUNRO, MHG ;

HIGA, T ;

SAKAI, R .

JOURNAL OF ORGANIC CHEMISTRY, 1988, 53 (17) :4127-4128

← 1 2 →