SYNTHESIS AND ANTIVIRAL ACTIVITY OF VARIOUS ESTERS OF 9-[(1,3-DIHYDROXY-2-PROPOXY)METHYL]GUANINE

被引：30

作者：

MARTIN, JC ^{[1
]}

TIPPIE, MA ^{[1
]}

MCGEE, DPC ^{[1
]}

VERHEYDEN, JPH ^{[1
]}

机构：

[1] SYNTEX RES CORP, INST BIOORGAN CHEM, PALO ALTO, CA 94304 USA

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1987年 / 76卷 / 02期

关键词：

D O I：

10.1002/jps.2600760221

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：180 / 184

页数：5

共 15 条

[1] ACTIVATION BY THYMIDINE KINASE AND POTENT ANTIHERPETIC ACTIVITY OF 2'-NOR-2'-DEOXYGUANOSINE (2'NDG) [J].

ASHTON, WT ;

KARKAS, JD ;

FIELD, AK ;

TOLMAN, RL .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1982, 108 (04) :1716-1721

[2] PRODRUGS OF 9-(BETA-D-ARABINOFURANOSYL)ADENINE .2. SYNTHESIS AND EVALUATION OF A NUMBER OF 2',3'-DI-O-ACYL DERIVATIVES AND 3',5'-DI-O-ACYL DERIVATIVES [J].

BAKER, DC ;

HASKELL, TH ;

PUTT, SR ;

SLOAN, BJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (03) :273-279

[3] PRODRUGS OF 9-BETA-D-ARABINOFURANOSYLADENINE .1. SYNTHESIS AND EVALUATION OF SOME 5'-(O-ACYL) DERIVATIVES [J].

BAKER, DC ;

HASKELL, TH ;

PUTT, SR .

JOURNAL OF MEDICINAL CHEMISTRY, 1978, 21 (12) :1218-1221

[4]

BENJAMIN EJ, UNPUB PARTITION COEF

[5]

CHAPLIN M, UNPUB

[6] UNIQUE SPECTRUM OF ACTIVITY OF 9-[(1,3-DIHYDROXY-2-PROPOXY)METHYL]-GUANINE AGAINST HERPESVIRUSES INVITRO AND ITS MODE OF ACTION AGAINST HERPES-SIMPLEX VIRUS TYPE-1 [J].

CHENG, YC ;

HUANG, ES ;

LIN, JC ;

MAR, EC ;

PAGANO, JS ;

DUTSCHMAN, GE ;

GRILL, SP .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (09) :2767-2770

[7]

FINNEY D J, 1971, P333

[8] ACTIVITY OF 9-(1,3-DIHYDROXY-2-PROPOXYMETHYL)GUANINE COMPARED WITH THAT OF ACYCLOVIR AGAINST HUMAN, MONKEY, AND RODENT CYTOMEGALOVIRUSES [J].

FREITAS, VR ;

SMEE, DF ;

CHERNOW, M ;

BOEHME, R ;

MATTHEWS, TR .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1985, 28 (02) :240-245

[9]

KORETZ SH, 1986, NEW ENGL J MED, V314, P801, DOI 10.1056/NEJM198603273141301

[10] 9-[(1,3-DIHYDROXY-2-PROPOXY)METHYL]GUANINE - A NEW POTENT AND SELECTIVE ANTIHERPES AGENT [J].

MARTIN, JC ;

DVORAK, CA ;

SMEE, DF ;

MATTHEWS, TR ;

VERHEYDEN, JPH .

JOURNAL OF MEDICINAL CHEMISTRY, 1983, 26 (05) :759-761

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