A CATALYTIC ASYMMETRIC MICHAEL REACTION OF SILYL ENOL ETHERS WITH ALPHA,BETA-UNSATURATED KETONES USING A CHIRAL TITANIUM-OXIDE

被引：61

作者：

KOBAYASHI, S

SUDA, S

YAMADA, M

MUKAIYAMA, T

机构：

来源：

CHEMISTRY LETTERS | 1994年 / 01期

关键词：

D O I：

10.1246/cl.1994.97

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In the presence of a catalytic amount of [(R)-1,1'-bi-2-naphthalenediolato(2-)O,O']oxotitanium, silyl enol ethers of thioesters reacted with alpha,beta-unsaturated ketones to afford the corresponding Michael adducts (1,5-dicarbonyl compounds) in high yields with moderate to high enantiomeric excesses.

引用

页码：97 / 100

页数：4

共 36 条

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