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CHARACTERIZATION AND USES OF MONOCLONAL-ANTIBODY DERIVED AGAINST DNA-BINDING DOMAIN OF THE ETS FAMILY OF GENES

被引：17
作者：
BHAT, NK [1 ]
PAPAS, TS [1 ]
机构：
[1] NCI, MOLEC ONCOL LAB, FREDERICK, MD 21702 USA
来源：
HYBRIDOMA | 1992年 / 11卷 / 03期
关键词：
D O I：
10.1089/hyb.1992.11.277
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
A monoclonal antibody recognizing ets proteins from a variety of species has been developed. This antibody recognizes ets1, ets2, erg, and other related proteins. It has a high affinity for the etsl protein. The epitope for the pan ets mAb consists of about 13 amino acids. This antibody can be used to isolate and characterize new members of ets gene family derived from a c-DNA expression library, as well as to identify other "ets motif" binding proteins.
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页码：277 / 294
页数：18
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