ROLE OF HYDROPHOBIC AND HYDROPHILIC FORCES IN PEPTIDE-PROTEIN INTERACTION - NEW ADVANCES

被引：29

作者：

CSERHATI, T ^{[1
]}

SZOGYI, M ^{[1
]}

机构：

[1] SEMMELWEIS UNIV MED,INST BIOPHYS,BUDAPEST,HUNGARY

来源：

PEPTIDES | 1995年 / 16卷 / 01期

关键词：

PEPTIDE-PROTEIN INTERACTIONS; HYDROPHOBIC AND HYDROPHILIC FORCES;

D O I：

10.1016/0196-9781(94)00134-R

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A considerable part of important biological processes is governed by the noncovalent association of peptides and proteins. Various types of intermolecular forces may be involved in the formation of these molecular assemblies. This review gives a brief account of the physicochemical bases of interactive forces, with special emphasis on their impact on various peptide-protein interactions; summarizes the newest biochemical and biophysical methods for the study of such interactions; and discusses the role of various hydrophilic and hydrophobic forces in peptide-protein interactions in various fields of life sciences, such as immunology, enzymology, receptor binding, and toxicology.

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页码：165 / 173

页数：9

相关论文

共 106 条

[11] DESTABILIZING EFFECTS OF REPLACING A SURFACE LYSINE OF CYTOCHROME-C WITH AROMATIC-AMINO-ACIDS - IMPLICATIONS FOR THE DENATURED STATE [J].

BOWLER, BE ;

MAY, K ;

ZARAGOZA, T ;

YORK, P ;

DONG, AC ;

CAUGHEY, WS .

BIOCHEMISTRY, 1993, 32 (01) :183-190

[12] SYNTHETIC MODEL PEPTIDES FOR APOLIPOPROTEINS .1. DESIGN AND PROPERTIES OF SYNTHETIC MODEL PEPTIDES FOR THE AMPHIPATHIC HELICES OF THE PLASMA APOLIPOPROTEINS [J].

BRASSEUR, R ;

VANLOO, B ;

DELEYS, R ;

LINS, L ;

LABEUR, C ;

TAVEIRNE, J ;

RUYSSCHAERT, JM ;

ROSSENEU, M .

BIOCHIMICA ET BIOPHYSICA ACTA, 1993, 1170 (01) :1-7

[13] SIDE CHAIN-BACKBONE HYDROGEN-BONDING CONTRIBUTES TO HELIX STABILITY IN PEPTIDES DERIVED FROM AN ALPHA-HELICAL REGION OF CARBOXYPEPTIDASE-A [J].

BRUCH, MD ;

DHINGRA, MM ;

GIERASCH, LM .

PROTEINS-STRUCTURE FUNCTION AND GENETICS, 1991, 10 (02) :130-139

[14] INTERACTION OF TROPONIN-I AND TROPONIN-C - USE OF THE 2-DIMENSIONAL TRANSFERRED NUCLEAR OVERHAUSER EFFECT TO DETERMINE THE STRUCTURE OF A GLY-110 INHIBITORY TROPONIN I PEPTIDE ANALOG WHEN BOUND TO CARDIAC TROPONIN-C [J].

CAMPBELL, AP ;

VANEYK, JE ;

HODGES, RS ;

SYKES, BD .

BIOCHIMICA ET BIOPHYSICA ACTA, 1992, 1160 (01) :35-54

[15]

CASCIERI MA, 1992, MOL PHARMACOL, V41, P1096

[16] ESSENTIAL GROUPS IN SYNTHETIC AGONIST PEPTIDES FOR ACTIVATION OF THE PLATELET THROMBIN RECEPTOR [J].

CHAO, BH ;

KALKUNTE, S ;

MARAGANORE, JM ;

STONE, SR .

BIOCHEMISTRY, 1992, 31 (27) :6175-6178

[17]

CHOPPIN J, 1992, PATHOL BIOL, V40, P257

[18]

COLBRAN JL, 1992, J BIOL CHEM, V267, P9589

[19] THROMBIN RECEPTOR ACTIVATING PEPTIDES - IMPORTANCE OF THE N-TERMINAL SERINE AND ITS IONIZATION STATE AS JUDGED BY PH-DEPENDENCE, NUCLEAR-MAGNETIC-RESONANCE SPECTROSCOPY, AND CLEAVAGE BY AMINOPEPTIDASE-M [J].

COLLER, BS ;

WARD, P ;

CERUSO, M ;

SCUDDER, LE ;

SPRINGER, K ;

KUTOK, J ;

PRESTWICH, GD .

BIOCHEMISTRY, 1992, 31 (47) :11713-11720

[20] SYNTHETIC MODEL PEPTIDES FOR APOLIPOPROTEINS .2. CHARACTERIZATION OF THE DISCOIDAL COMPLEXES GENERATED BETWEEN PHOSPHOLIPIDS AND SYNTHETIC MODEL PEPTIDES FOR APOLIPOPROTEINS [J].

CORIJN, J ;

DELEYS, R ;

LABEUR, C ;

VANLOO, B ;

LINS, L ;

BRASSEUR, R ;

BAERT, J ;

RUYSSCHAERT, JM ;

ROSSENEU, M .

BIOCHIMICA ET BIOPHYSICA ACTA, 1993, 1170 (01) :8-16

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