NOVEL FORMS OF PROTEIN GLYCOSYLATION

Glycosylation plays several important roles in glycoprotein function. Some of these roles, such as protein folding, protein stability and efficient intracellular transport, are more dependent simply on the presence of a saccharide, rather than on its exact structure. Other functions are directly related to specific saccharide structures. This article focuses on the occurrence and potential functions of such novel and specific glycosylations as O-N-acetylglucosamine, glucose-phosphate-mannose, N-acetylgalactosamine-bearing N-linked oligosaccharides, glucosylasparagine and glycosylations of epidermal growth factor modules.