SYNTHESIS OF SIALYL-TN ANTIGEN - REGIOSELECTIVE SIALYLATION OF A GALACTOSAMINE THREONINE CONJUGATE UNBLOCKED IN THE CARBOHYDRATE PORTION

被引：36

作者：

LIEBE, B ^{[1
]}

KUNZ, H ^{[1
]}

机构：

[1] UNIV MAINZ,INST ORGAN CHEM,D-55099 MAINZ,GERMANY

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 47期

关键词：

D O I：

10.1016/S0040-4039(00)78495-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Regioselective and stereocontrolled formation of the sialyl-Tn antigen conjugate 6 was achieved by reacting the NeuNAc-2-xanthate 2 with the GalNAc threonine acceptor 5 bearing three hydroxy groups. Complete deprotection afforded the sialyl-Tn antigen structure 11.

引用

页码：8777 / 8778

页数：2

共 12 条

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