THE CHEMICAL AND MICROBIOLOGICAL SYNTHESIS OF 14-HYDROXY-GIBBERELLINS

被引：6

作者：

FRAGA, BM

GARCIATELLADO, F

GONZALEZ, P

HERNANDEZ, MG

HANSON, JR

机构：

[1] UNIV LA LAGUNA,DEPT QUIM ORGAN,LA LAGUNA,SPAIN

[2] UNIV SUSSEX,SCH CHEM & MOLEC SCI,BRIGHTON BN1 9QJ,E SUSSEX,ENGLAND

来源：

TETRAHEDRON | 1992年 / 48卷 / 39期

关键词：

D O I：

10.1016/S0040-4020(01)86597-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Gibberellic acid has been transformed into 14beta-hydroxy-gibberellin A7 methyl ester via the rearrangement of an epoxy-beyergibberellin intermediate using a titanium-amide complex. The diterpene ent-beyer-15-en-19-ol has been transformed by chemical methods into ent-14alpha,19-dihydroxy-kaur-16-ene. The biotransformation of this compound with the fungus Gibberella fujikuroi gave 14beta-hydroxy-gibberellin A7, ent-7alpha, 14alpha, 19-trihydroxy-kaur-16-ene and ent-6alpha,7alpha, 14alpha-trihydroxy-kaur-16-en-19-oic acid. A minor gibberellin 14beta-hydroxy-GA14 was identified by GC-MS.

引用

页码：8491 / 8504

页数：14

共 26 条

[21] NEW METHOD FOR CONVERTING OXIRANES TO ALLYLIC ALCOHOLS BY AN ORGANOSILICON REAGENT [J].