A FORMAL TOTAL SYNTHESIS OF (+)-MACBECIN-I

被引：41

作者：

MARTIN, SF

DODGE, JA

BURGESS, LE

HARTMANN, M

机构：

[1] Department of Chemistry and Biochemistry, The University of Texas, Austin

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 04期

关键词：

D O I：

10.1021/jo00030a007

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A 21-step asymmetric synthesis of 23, which possesses the aryl subunit and the C(9)-C(21) segment of the stereochemically complex ansa chain of (+)-macbecin I (1), has been achieved. The subsequent conversion of 23 into 25, which was an advanced intermediate in Baker's total synthesis of 1, constitutes a formal synthesis of 1.

引用

页码：1070 / 1072

页数：3

共 40 条

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