SYNTHESIS OF ALKYNYLCYCLOOCTATETRAENES AND ALKYNYLCUBANES

被引：25

作者：

EATON, PE

STOSSEL, D

机构：

[1] Department of Chemistry, The University of Chicago, Chicago

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1991年 / 56卷 / 17期

关键词：

D O I：

10.1021/jo00017a028

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The couplings of a variety of iodocubanes with terminal acetylenes in refluxing NEt3 in the presence of Cu(I) and Pd(0) were examined. The products, isolated in about 50% yield, were not alkynylcubanes but were instead the first examples of alkynyl-1,3,5,7-cyclooctatetraenes. The first examples of alkynylcubanes (cubylacetylenes) were themselves synthesized in modest yield by Negishi's procedure from alkyl cubyl ketones. Cubylacetylenes were shown to be stable under Heck-like coupling conditions and potentially useful thereby for the introduction of the cubylacetylene moiety into complex systems.

引用

页码：5138 / 5142

页数：5

共 30 条

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