THE ROLE OF NATURAL-KILLER-CELLS IN IMMUNE SURVEILLANCE OF CANCER

被引：246

作者：

WHITESIDE, TL ^{[1
]}

HERBERMAN, RB ^{[1
]}

机构：

[1] UNIV PITTSBURGH,SCH MED,PITTSBURGH,PA 15213

来源：

CURRENT OPINION IN IMMUNOLOGY | 1995年 / 7卷 / 05期

关键词：

D O I：

10.1016/0952-7915(95)80080-8

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In the past year, a subset of natural killer cells designated 'A-NK cells' has been characterized. These immune cells appear to be able to enter solid tissues, migrate to sites of metastasis and eliminate malignant tissue cells, but spare normal tissue cells. They appear to be ideal surveillance cells, readily capable of upregulating antitumor functions in response to local activation signals.

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页码：704 / 710

页数：7

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