COVALENT INTERACTION OF REACTIVE METABOLITES WITH CYTOSOLIC COENZYME A AS MECHANISM OF HALOETHYLENE-INDUCED ACETONEMIA

被引：7

作者：

SIMON, P ^{[1
]}

BOLT, HM ^{[1
]}

FILSER, JG ^{[1
]}

机构：

[1] ZENT INST SEEL GESUNDHEIT,D-6800 MANNHEIM 1,FED REP GER

来源：

BIOCHEMICAL PHARMACOLOGY | 1985年 / 34卷 / 11期

关键词：

D O I：

10.1016/0006-2952(85)90319-3

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：1981 / 1986

页数：6

共 28 条

[11]

GUENGERICH FP, 1981, CANCER RES, V41, P4391

[12] EVIDENCE OF CHLOROETHYLENE OXIDE BEING THE REACTIVE METABOLITE OF VINYL-CHLORIDE TOWARDS DNA - COMPARATIVE STUDIES WITH 2,2'-DICHLORODIETHYLETHER [J].

GWINNER, LM ;

LAIB, RJ ;

FILSER, JG ;

BOLT, HM .

CARCINOGENESIS, 1983, 4 (11) :1483-1486

[13] INHALATION PHARMACOKINETICS BASED ON GAS UPTAKE STUDIES .2. PHARMACOKINETICS OF ACETONE IN RATS [J].

HALLIER, E ;

FILSER, JG ;

BOLT, HM .

ARCHIVES OF TOXICOLOGY, 1981, 47 (04) :293-304

[14]

JOCELYN PC, 1972, BIOCH SH GROUP, P63

[15] LIVER MICROSOMAL UPTAKE OF [C-14]VINYL CHLORIDE AND TRANSFORMATION TO PROTEIN ALKYLATING METABOLITES INVITRO [J].

KAPPUS, H ;

BOLT, HM ;

BUCHTER, A ;

BOLT, W .

TOXICOLOGY AND APPLIED PHARMACOLOGY, 1976, 37 (03) :461-471

[16] ALKYLATION OF RNA BY VINYL-CHLORIDE METABOLITES INVITRO AND INVIVO - FORMATION OF 1-N6-ETHENO-ADENOSINE [J].

LAIB, RJ ;

BOLT, HM .

TOXICOLOGY, 1977, 8 (02) :185-195

[17] DNA ALKYLATION BY VINYL-CHLORIDE METABOLITES - ETHENO DERIVATIVES OR 7-ALKYLATION OF GUANINE [J].

LAIB, RJ ;

GWINNER, LM ;

BOLT, HM .

CHEMICO-BIOLOGICAL INTERACTIONS, 1981, 37 (1-2) :219-231

[18]

LOWRY OH, 1951, J BIOL CHEM, V193, P265

[19]

LYNEN F, 1951, LIEBIGS ANN CHEM, V574, P1

[20] THE COMPOSITION OF THE KETOGLUTARATE DEHYDROGENASE COMPLEX [J].

MASSEY, V .

BIOCHIMICA ET BIOPHYSICA ACTA, 1960, 38 (03) :447-460

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