CAPILLARY ELECTROCHROMATOGRAPHY MASS-SPECTROMETRY - PRINCIPLES AND POTENTIAL FOR APPLICATION IN THE PHARMACEUTICAL-INDUSTRY

被引:62
作者
LANE, SJ
BOUGHTFLOWER, R
PATERSON, C
UNDERWOOD, T
机构
[1] Physical Sciences, Stevenage, Hertfordshire, SG1 2NY, Gunnels Wood Road
关键词
D O I
10.1002/rcm.1290091312
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Capillary electrochromatography (CEC) was coupled with electrospray (ESI) mass spectrometry and evaluated as an on-line high resolution technique for the separation and characterization of some typical pharmaceutical compound mixtures. Dispersion effects were observed and are discussed in the context of an optimized CEC/MS interface.
引用
收藏
页码:1283 / 1287
页数:5
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