NICOTINE-INDUCED POTENTIATION OF ETHANOL DISCRIMINATION

被引：30

作者：

SIGNS, SA ^{[1
]}

SCHECHTER, MD ^{[1
]}

机构：

[1] NE OHIO UNIV, COLL MED, DEPT PHARMACOL, ROOTSTOWN, OH 44272 USA

来源：

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR | 1986年 / 24卷 / 03期

关键词：

D O I：

10.1016/0091-3057(86)90589-7

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Rats were trained in a 2-lever, food-motivated operant task to discriminate intraperitoneal administration of ethanol (600 mg/kg) from vehicle. Dose-response curves for the ethanol cue were analyzed before and after pre-treatment of rats with intraperitoneal doses of 0.4 mg/kg or 0.2 mg/kg nicotine. Results demonstrate that nicotine potentiates ethanol-appropriate responding in test sessions. The results are discussed in light of the recognized correlation between smoking and alcohol intake.

引用

页码：769 / 771

页数：3

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