NICOTINE-INDUCED POTENTIATION OF ETHANOL DISCRIMINATION

被引：30

作者：

SIGNS, SA ^{[1
]}

SCHECHTER, MD ^{[1
]}

机构：

[1] NE OHIO UNIV, COLL MED, DEPT PHARMACOL, ROOTSTOWN, OH 44272 USA

来源：

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR | 1986年 / 24卷 / 03期

关键词：

D O I：

10.1016/0091-3057(86)90589-7

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Rats were trained in a 2-lever, food-motivated operant task to discriminate intraperitoneal administration of ethanol (600 mg/kg) from vehicle. Dose-response curves for the ethanol cue were analyzed before and after pre-treatment of rats with intraperitoneal doses of 0.4 mg/kg or 0.2 mg/kg nicotine. Results demonstrate that nicotine potentiates ethanol-appropriate responding in test sessions. The results are discussed in light of the recognized correlation between smoking and alcohol intake.

引用

页码：769 / 771

页数：3

共 16 条

[11] STATE-DEPENDENT LEARNING PRODUCED BY DEPRESSANT AND ATROPINE-LIKE DRUGS [J].

OVERTON, DA .

PSYCHOPHARMACOLOGIA, 1966, 10 (01) :6-6

[12]

Rosecrans JA., 1977, DISCRIMINATIVE STIMU, P155

[13] ENHANCEMENT OF [H-3]DOPAMINE RELEASE AND ITS [H-3]-LABELED METABOLITES IN RAT STRIATUM BY NICOTINIC DRUGS [J].

SAKURAI, Y ;

TAKANO, Y ;

KOHJIMOTO, Y ;

HONDA, K ;

KAMIYA, H .

BRAIN RESEARCH, 1982, 242 (01) :99-106

[14] APOMORPHINE INCREASES ETHANOL DISCRIMINATION [J].

SCHECHTER, MD .

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 1985, 22 (02) :179-182

[15] EXTENDED SCHEDULE TRANSFER OF ETHANOL DISCRIMINATION [J].

SCHECHTER, MD .

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 1981, 14 (01) :23-25

[16] ROLE OF TRAINING CONDITIONS IN DISCRIMINATION OF CENTRAL NERVOUS-SYSTEM STIMULANTS BY RATS [J].

STOLERMAN, IP ;

DMELLO, GD .

PSYCHOPHARMACOLOGY, 1981, 73 (03) :295-303

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