PHARMACOKINETICS OF PHENYLETHYLMALONAMIDE (PEMA) IN NORMAL SUBJECTS AND IN PATIENTS TREATED WITH ANTI-EPILEPTIC DRUGS

被引：11

作者：

COTTRELL, PR

STREETE, JM

BERRY, DJ

SCHAFER, H

PISANI, F

PERUCCA, E

RICHENS, A

机构：

[1] UNIV WALES WELSH NATL SCH MED,DEPT PHARMACOL & THERAPEUT,CARDIFF CF4 4XN,S GLAM,WALES

[2] DESITIN WERK CARL KLINKE GMBH,HAMBURG,FED REP GER

[3] NEW CROSS HOSP,POISONS UNIT,LONDON SE14 5ER,ENGLAND

来源：

EPILEPSIA | 1982年 / 23卷 / 03期

关键词：

D O I：

10.1111/j.1528-1157.1982.tb06196.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

引用

页码：307 / 313

页数：7

共 11 条

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GALLAGHER, BB ;

MATTSON, RH .

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[2] BENIGN FAMILIAL TREMOR TREATED WITH PRIMIDONE [J].

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[3] METABOLIC DISPOSITION OF PRIMIDONE AND ITS METABOLITES IN EPILEPTIC SUBJECTS AFTER SINGLE AND REPEATED ADMINISTRATION [J].

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BAUMEL, IP ;

MATTSON, RH .

NEUROLOGY, 1972, 22 (11) :1186-+

[4]

HAIDUKEWYCH D, 1980, CLIN CHEM, V26, P1537

[5] PRIMIDONE METABOLISM IN RENAL-INSUFFICIENCY AND ACUTE INTOXICATION [J].

HEIPERTZ, R ;

GUTHOFF, A ;

BERNHARDT, W .

JOURNAL OF NEUROLOGY, 1979, 221 (02) :101-104

[6]

HUNT R J, 1978, Drug Metabolism and Disposition, V6, P75

[7]

KAUFFMAN RE, 1977, CLIN PHARMACOL THER, V22, P200

[8] PLACENTAL-TRANSFER AND PHARMACOKINETICS OF PRIMIDONE AND ITS METABOLITES PHENOBARBITAL, PEMA AND HYDROXYPHENOBARBITAL IN NEONATES AND INFANTS OF EPILEPTIC MOTHERS [J].

NAU, H ;

RATING, D ;

HAUSER, I ;

JAGER, E ;

KOCH, S ;

HELGE, H .

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1980, 18 (01) :31-42

[9] BENIGN FAMILIAL TREMOR TREATED WITH PRIMIDONE [J].

OBRIEN, MD ;

UPTON, AR ;

TOSELAND, PA .

BRITISH MEDICAL JOURNAL, 1981, 282 (6259) :178-180

[10]

OXLEY J, 1980, ANTIEPILEPTIC THERAP

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