OF POSTULATES AND PECCADILLOES - ROBERT KOCH AND VACCINE (TUBERCULIN) THERAPY FOR TUBERCULOSIS

被引:19
作者
BURKE, DS
机构
[1] Division of Retrovirology, Walter Reed Army Institute of Research, Rockville, MD 20850, 13 Taft Court
关键词
KOCH; VACCINE THERAPY; TUBERCULOSIS; HIV;
D O I
10.1016/0264-410X(93)90354-Z
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In August 1890, Robert Koch dramatically announced that he had discovered a cure for tuberculosis, and the world rejoiced. The miracle substance was subsequently revealed to be tuberculin, inoculated as a 'vaccine therapy'. However, within a matter of months his claims were disputed and debunked, and his reputation was grievously damaged. The nationalistic pressures, professional jealousies and pecuniary interests that drove Koch's premature announcement are reviewed here and discussed in a context relevant to the development of therapeutic vaccines for human immunodeficiency virus infections.
引用
收藏
页码:795 / 804
页数:10
相关论文
共 50 条
[1]  
BONIME E, 1917, TUBERCULIN VACCINE T
[2]  
BROCK TD, 1988, R KOCH LIFE MED BACT, P205
[3]  
BROCK TD, 1988, R KOCH LIFE MED BACT, P169
[4]  
BROCK TD, 1988, R KOCH LIFE MED BACT, P232
[5]  
Brock Thomas D., 1988, R KOCH LIFE MED BACT
[6]  
BURKE DS, IN PRESS VACCINE
[7]  
CALDWELL M, 1988, LAST CRUSADE WAR CON, P161
[8]  
COCHRANE AWR, 1915, GUIDE USE TUBERCULIN
[9]  
COLLINS FM, 1991, REV INFECT DIS, V13, P940
[10]   DELAYED-TYPE HYPERSENSITIVITY AND CELL-MEDIATED-IMMUNITY IN THE PATHOGENESIS OF TUBERCULOSIS [J].
DANNENBERG, AM .
IMMUNOLOGY TODAY, 1991, 12 (07) :228-233