DIFFERENTIAL EXPRESSION OF THE INWARDLY-RECTIFYING K-CHANNEL ROMK1 IN RAT-BRAIN

被引：24

作者：

KENNA, S

ROPER, J

HO, K

HEBERT, S

ASHCROFT, SJH

ASHCROFT, FM

机构：

[1] UNIV OXFORD, PHYSIOL LAB, OXFORD OX1 3PT, ENGLAND

[2] JOHN RADCLIFFE HOSP, NUFFIELD DEPT CLIN BIOCHEM, OXFORD OX3 9DU, ENGLAND

[3] HARVARD UNIV, BRIGHAM & WOMENS HOSP,SCH MED,DEPT MED,DIV RENAL, BOSTON, MA 02115 USA

来源：

MOLECULAR BRAIN RESEARCH | 1994年 / 24卷 / 1-4期

基金：

英国惠康基金;

关键词：

ROMK1; ATP-SENSITIVE K-CHANNEL; RAT BRAIN;

D O I：

10.1016/0169-328X(94)90150-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We have investigated the distribution of the inwardly-rectifying K-channel ROMK1 in rat brain using Northern blotting and in situ hybridization. High levels of expression were found in cortex and hippocampus but not in substantia nigra, ventromedial hypothalamus, cerebellum or striatum. PCR primers generated against ROMK1 amplified a 300 bp cDNA fragment from cortex and hippocampus identical in sequence to ROMK1.

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页码：353 / 356

页数：4

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